Aging is an inevitable natural process of organisms, characterized by the gradual decline of body structure and function over time. This process is complex and easily affected by a variety of external factors such as the environment. In order to accurately grasp the pace of aging, scientists have abandoned the traditional rough measurement method of years or days and instead focused on a more delicate time dimension, striving to achieve subtle insights into the aging process.
In this exploration, scientists have developed a series of aging biomarkers with ingenuity, among which DNA methylation patterns are particularly eye-catching. As a key epigenetic regulatory mechanism, DNA methylation patterns can accurately map the current aging appearance of an individual, not only revealing the dynamic changes of genetic information during the aging process, but also becoming an indispensable precision tool in aging science research. Through the in-depth analysis of these biomarkers, scientists have been able to glimpse the molecular mechanisms behind aging, opening up new paths for delaying aging and promoting healthy aging.
In the vast starry sky of anti-aging science, NMN (nicotinamide mononucleotide) once streaked across like a dazzling meteor, and as a precursor of NAD+ (nicotinamide adenine dinucleotide), it inspired the research enthusiasm of countless scientists. However, as time went by, another brighter star, AKG (α-ketoglutaric acid), gradually emerged and won wider recognition in the field of anti-aging with its unique charm and scientific basis. This article will combine the research results of international authoritative medical journals and actual cases to explore in depth why AKG can surpass NMN and become the new darling in the field of anti-aging.
In a study published in the journal Nature Metabolism, scientists elaborated on the mechanism of action of AKG in energy metabolism, mitochondrial function and anti-aging. The study pointed out that AKG can directly promote the tricarboxylic acid cycle, increase energy output in cells, and thus enhance the overall vitality of cells. In addition, the journal Cell Metabolism also published research results on AKG in promoting collagen synthesis and improving skin elasticity, further confirming its potential in the field of anti-aging.
Case 1: Reversing the signs of aging
A clinical study from Japan provides us with a vivid example. A middle-aged woman who has long been concerned about anti-aging, after taking AKG supplements for half a year, not only did her skin condition improve significantly, becoming tighter and more elastic, but her overall physical fitness and mental state also improved significantly. By comparing the physiological indicators before and after the experiment, the researchers found that the woman's mitochondrial function was significantly enhanced, which is closely related to the role of AKG in promoting energy metabolism.
Case 2: Guardian of neurological health
Another study from the United States focused on the role of AKG in neuroprotection. An elderly person with mild cognitive impairment had significantly improved cognitive ability, memory and attention after receiving AKG treatment. The researchers observed through brain imaging technology that the patient's neuronal mitochondrial function was restored, which provides strong support for AKG in the prevention and treatment of neurodegenerative diseases.
AKG's unique advantages
Multi-dimensional anti-aging effects
Unlike NMN, which mainly fights aging by increasing NAD+ levels, AKG has a more comprehensive anti-aging effect. It can not only promote energy metabolism and enhance mitochondrial function, but also improve the body's aging state from multiple dimensions by affecting amino acid metabolism and promoting collagen synthesis.
Higher biocompatibility and safety
As a naturally occurring metabolite in the human body, AKG performs well in terms of biocompatibility and safety. It can be directly absorbed and utilized by the human body without going through a complex conversion process, reducing the potential risk of adverse reactions. This makes the application of AKG in the anti-aging field safer and more reliable.
Wide range of health benefits
In addition to anti-aging, AKG also shows a wide range of health benefits in promoting nerve health, enhancing immunity, etc. These additional health benefits make the application of AKG in the field of anti-aging even more attractive.
With the continuous deepening of scientific research and the continuous advancement of technology, the application prospects of AKG in the field of anti-aging will be broader. We look forward to more high-quality research in the future to reveal more mysteries of AKG, and we also look forward to it being combined with other anti-aging strategies such as NMN to contribute more wisdom and strength to human health and longevity. In this race against time, AKG has undoubtedly demonstrated strong competitiveness and unlimited possibilities.
Lao Mi has recently been supplementing his use of a very popular AKG product on the market, which is also a highly-watched anti-aging product. The feeling is very good, and it is no exaggeration to describe it as wonderful. Later, I will share with you more personal experiences after using it by myself, my family and friends!
This is a dietary supplement. It is not a medicine, nor a health product. You must pay attention to the fact that NAD+ cannot be absorbed and utilized by the small intestine through oral NAD+ due to its large molecular weight. Most of the products on the market that directly supplement NAD+ have a bioavailability of basically 0, which is equivalent to eating in vain. What Lao Mi eats is actually an induction factor, not a direct supplement of NAD+. It is through the induction factor that the body's NAD+ is induced to maintain a certain level. Lao Mi can't explain the specific technology in a few words. You can consult the relevant authoritative information by yourself. It aims to fight aging and improve various chronic diseases through scientific means. This product uses α-ketoglutaric acid (AKG) as the main ingredient and achieves anti-aging effects through various channels. It has not only passed the verification of animal experiments and clinical trials, but also obtained a number of international authoritative certifications, such as the US NSF, FDA and EU GMP, etc., to ensure its safety and effectiveness.
The main effects are:
Anti-aging: It significantly delays the cell aging process by regulating the mTOR signaling pathway, promoting autophagy, improving protein metabolism abnormalities, and regulating epigenetics. In addition, it can promote collagen synthesis, support cell detoxification, help restore normal calcium concentration levels in the blood, accelerate wound healing, and promote muscle tissue repair.
Improve chronic diseases: Clinical trials have shown that it has significant improvement effects on a variety of chronic diseases, including but not limited to osteoporosis, neurodegenerative diseases (such as Parkinson's disease), cardiovascular diseases, diabetes, and cancer. It fundamentally solves the root causes of chronic diseases by activating longevity proteins in the body and repairing damaged DNA.
Improve immunity: It can enhance the activity and number of immune cells, improve the body's overall immunity, and thus help the body better resist diseases and infections.
Promotes health: This product also has benefits such as promoting the metabolism of blood sugar and fat in the body, supporting healthy brain cognitive function, etc., which helps maintain the overall health of the human body.
The anti-aging effect is supported by scientific research. For example, in 2014, the top journal Nature first reported that aging can be delayed by inhibiting the activity of mTOR; in studies of human osteosarcoma cells, it was also proven that it can promote autophagy; in addition, it can participate in the synthesis of amino acids, reduce the occurrence of abnormal protein metabolism, and participate in epigenetic regulation processes such as DNA demethylation.
Clinical trials have further confirmed its safety and effectiveness. For example, the Phase I human clinical trial report commissioned by California NewMed Hospital showed that it has a significant curative effect on a variety of chronic disease symptoms such as insomnia, memory loss, renal failure, and stroke sequelae, and has an excellent conditioning effect on sequelae such as shortness of breath, fatigue, and cough caused by the new coronavirus.
With its remarkable efficacy and safety, it has won wide attention and praise in the market. Many users said that they felt a significant improvement in their physical condition after taking it, such as more energy, tighter and more elastic skin, etc. At the same time, the product has also been recognized and supported by many authoritative institutions and experts.
To sum up, this is a scientific, safe and effective anti-aging product. It achieves anti-aging effects and improves the symptoms of various chronic diseases through multiple pathways. It is an ideal choice for people who pursue health and longevity.
